Researchers determined that current data uphold the 2004 recommendation of the U.S. Preventive Services Task Force (USPSTF) that routine screening for testicular cancer in asymptomatic men is not warranted. These findings were recently published in the journal Annals of Internal Medicine.
The testicles are located inside the scrotum (a sac of loose skin that lies directly under the penis). Testicular cancer—also called germ cell cancer—occurs in the tissues of one or both testicles. Testicular cancers are relatively rare but highly curable and occur predominantly in young and middle-aged males. The incidence of testicular cancer has been increasing in many western countries. Between 1975 and 2002, the rate of testicular cancer doubled in the United States. In 2004, the USPSTF concluded that screening men without symptoms for testicular cancer was not beneficial. The USPSTF recently evaluated more recent data to determine whether or not changes for testicular cancer screening guidelines were warranted.
Researchers evaluated published studies that included randomized trials, meta-analyses, systemic reviews, as well as additional databases to determine the risks and benefits of testicular cancer screening. Upon review of the available data, the researchers determined that the 2004 recommendation of the USPSTF that testicular cancer screening in asymptomatic men was not warranted was still valid. No new risks or benefits of screening were established.
These screening recommendations only apply to asymptomatic men (men without testicular symptoms). Men with testicular symptoms are advised to discuss the symptoms with their healthcare provider. .
 Lin K and Sharangpani R. Clinical Guidelines: Screening for Testicular Cancer: An Evidence Review for the U.S. Preventive Services Task Force. Annals of Internal Medicine. 2010;153:396-399.