Finding Your Energy Again: Understanding and Managing Cancer-Related Fatigue

Feeling constantly tired during cancer treatment is more than just being worn out—it’s a common and treatable part of the cancer journey. Learn what causes cancer-related fatigue, how to talk to your care team, and simple ways to boost energy through nutrition, movement, and stress relief. Small changes can make a big difference in how…

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Feeling unusually tired or drained during cancer treatment is extremely common. In fact, about three out of four people going through cancer therapy experience fatigue. This isn’t just ordinary tiredness—it can be a deep, ongoing exhaustion that makes it hard to work, focus, or even enjoy simple activities.

Fatigue affects quality of life and can influence how well treatment works. Talking with your care team about fatigue is important so you can find the right ways to manage it and feel more like yourself again.

What Fatigue Feels Like

Fatigue is more than just feeling sleepy. You might notice:

  • A constant lack of energy or motivation
  • Trouble concentrating or staying alert
  • Weakness or dizziness
  • Difficulty recovering energy even after rest
  • Less interest in activities or people you enjoy

Because fatigue is invisible and varies from person to person, it can be hard to describe. Some people think they should be able to “push through,” but cancer-related fatigue is a medical symptom that deserves attention and care.

What Causes Fatigue

Fatigue during cancer treatment often has several causes happening at once, including:

  • Anemia: Many treatments can lower red blood cell counts, leading to anemia, which causes fatigue, shortness of breath, or weakness.
  • Infection: Fighting infections uses up energy and can increase tiredness.
  • Medications: Drugs for pain, nausea, or anxiety can make you feel drowsy or sluggish.
  • Poor nutrition: Loss of appetite or early fullness can make it hard to get enough nutrients and energy.
  • Too much or too little rest: Staying in bed too long can actually lower energy levels. Gentle daily activity, such as short walks or stretching, can help.
  • Stress and emotions: Pain, worry, or depression can interrupt sleep and drain energy.
  • Other health issues: Conditions like thyroid problems, heart or kidney disease, or diabetes can make fatigue worse.

If you notice new or worsening fatigue, tell your doctor. A treatable cause, such as anemia or a medication side effect, may be identified and managed.

Ways to Manage Fatigue

There isn’t one single solution for fatigue, but several strategies can make a big difference:

  • Treat anemia: If anemia is contributing to fatigue, your doctor might recommend treatments such as red blood cell transfusions or medications that help your body make more red blood cells.
  • Eat well: Keep your body fueled with protein-rich foods like eggs, beans, cheese, or lean meat. If eating is hard, ask for a dietitian’s help and aim for small, frequent snacks and plenty of liquids.
  • Conserve energy: Focus on the most important tasks, pace yourself, and ask for help with chores or errands. Schedule rest throughout the day—but try not to stay inactive for long periods.
  • Exercise gently: Light movement, such as walking or stretching, can help improve stamina, circulation, and mood over time.
  • Review medications: Ask your doctor or pharmacist whether any of your medications could be causing fatigue.
  • Manage stress: Counseling, support groups, breathing exercises, and relaxation techniques can reduce emotional fatigue.

Complementary Approaches

Many people also find relief through complementary therapies used alongside medical treatment. Massage, acupuncture, yoga, and mindfulness-based relaxation can ease tension and boost energy. Studies have shown that these methods are safe and can help reduce fatigue and improve emotional well-being when guided by experienced practitioners.

Nutrition and Eating Tips When You’re Too Tired to Eat

Cancer fatigue often makes eating feel like too much effort, but nutrition is vital for maintaining strength and recovery. Small adjustments can help:

  • Ask friends or family to help with meals or grocery runs.
  • Eat or sip something every hour—even a few bites count.
  • Keep easy, high-protein snacks like yogurt, nuts, or cheese near your bed or chair.
  • Try soft or ready-to-eat options like smoothies, pudding, or nutritional drinks if chewing or cooking feels hard.
  • Drink eight to ten glasses of fluid a day to prevent dehydration.

There are no miracle “energy foods,” and stimulants or herbal supplements like ginseng or guarana can be unsafe during cancer treatment. Stick with balanced meals and hydration instead.

Understanding Anemia and Its Treatment

Anemia occurs when your blood contains too few red blood cells to carry oxygen efficiently. This is common in people with lung, breast, ovarian, or blood cancers and may occur as a result of chemotherapy.

Doctors monitor hemoglobin levels to identify anemia and may treat it with medication or transfusions. Treating anemia can reduce fatigue, improve energy, and enhance overall quality of life.

References:

  1. Symposium at 2003 annual meeting of the Oncology Nursing Society. Are Oncology Nurses the Strongest Link? Effective management of chemotherapy-associated neuropathy, anemia, and neutropenia. Gillespie, T. presenter of anemia section. May 1, 2003.
  2. Cella D, Peterman A, Passik S, et al. Progress toward guidelines for the management of fatigue. Oncology. 1998. 369-377.
  3. West C, Paul S, Miaskowkski C, et al. Symptom clusters predict fatigue severity in oncology outpatients. Proceedings from the 2003 annual meeting of the Oncology Nursing Society. Abstract #136.
  4. Byar K, Berger A. Women receiving adjuvant chemotherapy for breast cancer: impact on quality of life and fatigue. Proceedings from the 2003 annual meeting of the Oncology Nursing Society. Abstract #142.
  5. Dunphy FR, Harrison BR, Dunleavy TL, et al. Erythropoietin reduces anemia and transfusions:a randomized trial with or without erythropoietin during chemotherapy. Cancer. 1999;86:1362-1367.
  6. Glaspy JA, Jadeja J, Justice G. Optimizing the management of anemia in patients with cancer: a randomized, active-controlled study investigating the dosing of darbepoetin alfa (abstract). Proceedings of the American Society of Clinical Oncology 38th annual meeting; May 18-21, 2002. Abstract 1446.
  7. Kotasek D, Albertson M, Mackey J. Randomized, double-blind, placebo-controlled, dose-finding study of darbepoetin alfa administered once every 3 (Q3W) or 4 (Q4W) weeks in patients with solid tumors [abstract]. Proceedings of the American Society of Clinical Oncology 38th annual meeting; May 18-21, 2002. Abstract 1421.
  8. Complementary and Alternative Methods for Cancer Management. American Cancer Society Web site. Available here.
  9. Deng G, Cassileth BR, Yeung KS. Complementary therapies for cancer-related symptoms. Journal of Supportive Oncology. 2004;2(5):419-26.
  10. Acupuncture: Questions and Answers About Acupuncture. National Cancer Institute Web site. Available here.
  11. Fatigue. National Cancer Institute Web site. Available here.
  12. NCCN Guidelines. Available at:
    nccn.org/patient_gls/asp/ASP_Script_showTree/SVGAframeset.asp?pg=fatigueidchart=6bkg=.
  13. Amorajabi M, Tchekmedyian S, Kallich J. Patient-reported depression and anxiety in patients with cancer improves following reduction in anemia-related fatigue with darbepoetin alfa therapy. Proceedings from the 2003 annual meeting of the Oncology Nursing Society. Abstract # 118.
  14. Proceedings of American Society of Clinical Oncology, Vol 18, Abstract 2217, 1999

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