Smoking Increases Bladder Cancer Risk
by Dr. C.H. Weaver M.D. (05/2018)
According to a study published in the journal Cancer Epidemiology, Biomarkers and Prevention, risk of bladder cancer increases with duration and amount of smoking.
The bladder is an organ in the lower abdomen that stores urine after it is released from the kidneys until it is passed out of the body. Bladder cancer is the fifth most common type of cancer in the United States and causes approximately 13,000 deaths annually.
Cure rates remain high for bladder cancer that is detected and treated early?prior to spread from its site of origin. Cure rates fall dramatically, however, if the cancer is detected at a more advanced stage.
Risk of bladder cancer increases with age, and men are more commonly affected than women. Because smoking has been linked with an increased risk of bladder cancer, researchers continue to evaluate specific aspects of smoking in relation to bladder cancer risk.
To further evaluate the link between smoking and bladder cancer, researchers in Spain conducted a study among 1,219 patients with newly diagnosed bladder cancer and 1,271 individuals without bladder cancer.
- Current smoking increased the risk of bladder cancer by more than seven-fold in men and by roughly five-fold in women.
- Former smokers also had an increased risk of bladder cancer, but the strength of the link was stronger for men than for women.?
- Risk of bladder cancer increased with duration and amount smoked.
- After accounting for duration of smoking, risk of bladder cancer did not vary significantly by type of tobacco (black vs. blond). However, the decline in risk after quitting smoking was greater for smokers of blond tobacco than smokers of black tobacco.
- Compared to men who inhaled into the mouth, men who inhaled into the throat or chest had an increased risk of bladder cancer.
- Most of the difference in bladder cancer rates between men and women in Spain appeared to be due to differences in smoking.
This study suggests a strong link between smoking and bladder cancer.
Reference: Samanic C, Kogevinas M, Dosemeci M et al. Smoking and Bladder Cancer in Spain: Effects of Tobacco Type, Timing, Environmental Tobacco Smoke, and Gender. Cancer Epidemiology, Biomarkers and Prevention . 2006;15:1348-1354.
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