Myeloproliferative Neoplasms: Making Progress in Polycythemia Vera and Myelofibrosis

Myeloproliferative neoplasms (MPN) are a related group of blood cancers. In these disorders, the bone marrow cells that produce blood cells develop and function abnormally. The three main types of MPN are polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). In addition to developing on its own, myelofibrosis may also develop as a result of ET or PMF.

Myeloproliferative neoplasms are most common in older adults. Out of every 100,000 people in the United States, an estimated 44 to 57 people have PV, and a similar number have ET. Myelofibrosis is less common, affecting 4 to 6 people per 100,000.

An important advance in our understanding of MPN is the identification of certain gene mutations that contribute to these conditions.  In the case of myelofibrosis, this discovery has contributed to the development of new drugs to treat the condition. The last year marked important progress in the management of PV and myelofibrosis with a new treatment option now available for PV patients.

CancerConnect News coverage of advances in the management of MPNs included the following key developments:

2014 Ask the MPN Expert

2014 Research and FDA News in Polycythemia Vera

2014 Research News in Myelofibrosis

2014 Research News in Essential Thrombocythemia

Current Myeloproliferative Neoplasm News


Knowledge is power. Are you facing a new diagnosis, recurrence, living with metastatic disease, or supporting a loved one through their cancer journey?

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