General Neuroblastoma


Improved Survival with Busulphan-Melphalan Chemotherapy in Pediatric Neuroblastoma (June 8, 2011)

Treatment with high doses of the chemotherapy combination including busulphan and melphalan significantly improves survival and reduces cancer progression among pediatric patients with high-risk neuroblastoma.... Continue Reading

Reduced Chemotherapy Regimen May Be Effective in Neuroblastoma (November 10, 2010)

According to results of a Phase III clinical trial, patients with intermediate-risk neuroblastoma may be effectively treated with reduced doses of chemotherapy given over a shorter period. These findings... Continue Reading

Neuroblastoma Survival has Improved (May 11, 2010)

Between 1979 and 2005, ten-year overall survival with neuroblastoma improved from 34.9% to 65%. The results of this study, conducted in Italy, were published in the Journal of Clinical Oncology. Neuroblastoma... Continue Reading

Gene Expression Predicts Neuroblastoma Outcome (June 30, 2009)

Among children with neuroblastoma, a test that assesses the activity of several genes in a sample of tumor tissue provides information about the patient’s prognosis and may help guide treatment decisions.... Continue Reading

Genetic Variation Associated with Risk of Neuroblastoma (May 9, 2008)

Genetic Variation Associated with Risk of Neuroblastoma Individuals with a common genetic variation (change in DNA) on the chromosome band 6p22 have a significantly increased risk of developing neuroblastoma,... Continue Reading

Vitamins During Pregnancy Decrease Childhood Cancer Risk (February 23, 2007)

Vitamins During Pregnancy Decrease Childhood Cancer Risk According to an early online publication in the journal Clinical Pharmacology and Therapeutics, children of mothers who take vitamins during pregnancy... Continue Reading

Gene Expression and Outcomes with Standard Therapy in Neuroblastoma (September 6, 2006)

Gene Expression and Outcomes with Standard Therapy in Neuroblastoma According to an article recently published in the Journal of the National Cancer Institute, gene expression profiling may help predict... Continue Reading

Two Autologous Stem Cell Transplants Effective for High-risk Neuroblastoma (August 21, 2006)

Two Autologous Stem Cell Transplants Effective for High-risk Neuroblastoma According to an article recently published in the Journal of Clinical Oncology, treatment including induction chemotherapy, surgery,... Continue Reading

Chromosome Abnormalities Affect Outcomes of Neuroblastoma (November 29, 2005)

Chromosome Abnormalities Affect Outcomes of Neuroblastoma According to a recent article published in the New England Journal of Medicine, patients with neuroblastoma who have chromosomal abnormalities... Continue Reading

Good Prognosis for Neuroblastoma Patients Diagnosed Before 18 Months of Age (September 20, 2005)

Good Prognosis for Neuroblastoma Patients Diagnosed Before 18 Months of Age According to three studies published together in the Journal of Clinical Oncology, children between the ages of 12 and 18 months... Continue Reading

Chemotherapy and Autologous Stem Cell Transplant Improve Outcome for Children with Neuroblastoma (August 23, 2005)

Chemotherapy and Autologous Stem Cell Transplant Improve Outcome for Children with Neuroblastoma Children and adolescents with high-risk neuroblastoma have better outcomes after treatment with high-dose... Continue Reading

Chromosomal Changes May Help Predict Pediatric Neuroblastoma Outcomes (May 20, 2005)

Chromosomal Changes May Help Predict Pediatric Neuroblastoma Outcomes Researchers affiliated with the Children’s Oncology group recently reported that changes associated with chromosome 11q are a... Continue Reading

Vitamin Supplementation During Pregnancy Decreases Incidence of Neuroblastoma in Children (August 28, 2002)

Vitamin Supplementation During Pregnancy Decreases Incidence of Neuroblastoma in Children According to a recent article in the journal Epidemiology, women who supplement with daily vitamins and... Continue Reading

Screening for Neuroblastoma Does Not Appear to Reduce Mortality (April 29, 2002)

Screening for Neuroblastoma Does Not Appear to Reduce Mortality According to recent articles published in The New England Journal of Medicine, general screening of infants and toddlers for neuroblastoma... Continue Reading

F38 and GM-CSF Produce Anti-Cancer Responses in Patients with Non-Progressive Neuroblastoma (February 14, 2002)

F38 and GM-CSF Produce Anti-Cancer Responses in Patients with Non-Progressive Neuroblastoma A recent article published in the Journal of Clinical Oncology suggests that the combination of F38,... Continue Reading

New Blood Test May Help Determine Treatment Options for Neuroblastoma (February 14, 2002)

New Blood Test May Help Determine Treatment Options for Neuroblastoma A new blood test for patients diagnosed with neuroblastoma may help determine which patients are at the greatest risk for a cancer... Continue Reading

New Monoclonal Antibody Appears Promising for Treatment of Neuroblastoma (February 14, 2002)

New Monoclonal Antibody Appears Promising for Treatment of Neuroblastoma A novel monoclonal antibody, called ch14.18, has shown promising results in the initial phases of clinical trials for the treatment... Continue Reading

Surgery Alone Remains Primary Treatment for Stage I and II Neuroblastoma (February 14, 2002)

Surgery Alone Remains Primary Treatment for Stage I and II Neuroblastoma Neuroblastoma is a type of cancerous tumor that can occur in children, most often in those younger than 2 years old. This cancer... Continue Reading

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