General Bone Cancer


Xgeva Safe and Effective for Giant Cell Tumor of the Bone (August 6, 2013)

The planned interim results of an international, open-label, phase 2 clinical trial published in the Lancet Oncology indicate that Xgeva® (denosumab) is safe and effective in the treatment of giant cell... Continue Reading

Xgeva Approved for Treatment of Giant Cell Tumor of the Bone (July 17, 2013)

The U.S. Food and Drug Administration (FDA) has expanded the approved use of Xgeva® (denosumab) to include the treatment of adults and some adolescents with giant cell tumor of the bone (GCTB). Giant... Continue Reading

Xgeva Reduces Giant-cell Tumor of the Bone (October 2, 2012)

Xgeva® (denosumab) significantly reduced or eliminated tumor giant cells in patients with giant-cell tumor of the bone and also increased new bone formation, according to the results of a phase II study... Continue Reading

Aspirin Continues to Look Promising for Cancer Prevention (March 26, 2012)

A combined analysis of 51 randomized trials found that daily aspirin use reduces the risk of new cancer diagnoses as well as the risk of cancer death. These results were published in The Lancet. A growing... Continue Reading

Xgeva Delays Onset of Bone Metastases (September 27, 2011)

Among men with prostate cancer that has stopped responding to hormonal therapy, the bone drug Xgeva™ (denosumab) delayed the spread of cancer to the bones. These results were presented at the 2011 European... Continue Reading

Stay on Top of Your Family History of Cancer (July 15, 2011)

People who are at high risk of cancer as a result of their family history may be advised to undergo earlier or more intensive cancer screening. Because family history of cancer can change over time, it’s... Continue Reading

Denosumab Active Against Giant Cell Tumor of Bone (February 11, 2010)

In a Phase II clinical trial, denosumab produced high rates of tumor response among patients with recurrent or unresectable giant cell tumors of bone. These results were published in Lancet Oncology. Denosumab... Continue Reading

Denosumab Reduces the Risk of Bone Fractures (September 17, 2008)

Denosumab Reduces the Risk of Bone Fractures According to the results of a Phase III clinical trial, treatment with denosumab significantly reduces the risk of vertebral and hip fractures among postmenopausal... Continue Reading

Shortened Interval Between Chemotherapy Cycles Does Not Improve Survival with Osteosarcoma (January 23, 2007)

Shortened Interval Between Chemotherapy Cycles Does Not Improve Survival with Osteosarcoma According to the results of a study published in the Journal of the National Cancer Institute, osteosarcoma... Continue Reading

Heart Dysfunction Continues Long After Treatment with Adriamycin® (July 21, 2006)

Heart Dysfunction Continues Long After Treatment with Adriamycin® According to results published in the Annals of Oncology, childhood cancer survivors with bone cancer who were treated with Adriamycin®... Continue Reading

Chemotherapy Combination Produces Promising Results in Ewing’s Sarcoma (April 5, 2006)

Chemotherapy Combination Produces Promising Results in Ewing’s Sarcoma Among patients with high-risk Ewing’s sarcoma family of tumors (ESFT), treatment with an intensified chemotherapy regimen... Continue Reading

Computed Tomography (CT) Misses Large Portion of Cancer Spread to Lung in Osteosarcoma (February 7, 2006)

Computed Tomography (CT) Misses Large Portion of Cancer Spread to Lung in Osteosarcoma According to a recent article published in the Journal of Pediatric Surgery, computed tomograhy (CT) scans miss over... Continue Reading

Surgical Removal of Cancer Spread to the Lung Significantly Improves Survival in Osteosarcoma (February 7, 2006)

Surgical Removal of Cancer Spread to the Lung Significantly Improves Survival in Osteosarcoma According to a recent article published in the Journal of Pediatric Surgery, the surgical removal of cancer... Continue Reading

Cisplatin Benefits Patients with Metastatic Osteosarcoma (January 12, 2006)

Cisplatin Benefits Patients with Metastatic Osteosarcoma A comparison of two clinical trials suggests that the chemotherapy drug cisplatin is more effective against metastatic osteosarcoma than the chemotherapy... Continue Reading

Type of Treatment Influences Survival with Radiation-Induced Osteosarcoma (December 2, 2005)

Type of Treatment Influences Survival with Radiation-Induced Osteosarcoma Aggressive treatment appears to significantly improve survival among patients who develop radiation-induced osteosarcoma following... Continue Reading

Osteosarcoma Patients with Recurrent Lung Metastases May Benefit from Additional Surgery (November 16, 2005)

Osteosarcoma Patients with Recurrent Lung Metastases May Benefit from Additional Surgery Osteosarcoma frequently spreads to the lungs, and in some cases these lung metastases can be surgically removed.... Continue Reading

Intra-Arterial Chemotherapy May Improve Survival in Osteosarcoma (September 12, 2005)

Intra-Arterial Chemotherapy May Improve Survival in Osteosarcoma According to a recent article published in the journal Clinical Orthopaedics and Related Research, intra-arterial chemotherapy prior to... Continue Reading

Short and Long Courses of Radiation Reduce Bone Pain (June 17, 2005)

Short and Long Courses of Radiation Reduce Bone Pain A recent article in the Journal of the National Cancer Institute reports that a short course of radiation is equally effective as a standard 10-course... Continue Reading

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