Stem Cell Transplant


Duration of Blood Storage Does Not Affect Outcomes for Patients Requiring Blood Transfusions (December 1, 2016)

The length of time that blood is stored prior to a blood transfusion, within normal ranges, does not appear to affect mortality among patients requiring transfusions. These results were recently published... Continue Reading

Defitelio® Approved for Life-Threatening Complication of Stem Cell Transplant (March 30, 2016)

The United States Food and Drug Administration (FDA) has approved Defitelio® (defibrotide sodium) for the treatment of hepatic veno-occlusive disease (VOD) following a stem cell transplant. Defitelio... Continue Reading

Myeloablative Treatment Regimens Superior to Reduced Intensity Treatment for AML and MDS Patients Undergoing Stem Cell Transplant (December 30, 2015)

Hematopoietic Stem Cell Transplant (SCT) is a standard and potentially curative treatment for individuals with myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). Historically only high dose... Continue Reading

Data Back Stem Cell Transplant as Cure for Sickle Cell (December 28, 2015)

A recent report suggests that over 90% of patients with sickle cell disease treated with an HLA-matched sibling stem-cell transplant (SCT) survive, free of disease, 3 years after treatment and are probably... Continue Reading

Prospective Study Shows Age Doesn’t Affect Survival Outcomes in Patients with Myelodysplastic Syndrome (MDS) Who Receive a Hematopoietic Cell Transplant (HCT) (December 14, 2015)

Results from a prospective study of 1,280 patients with myelodysplastic syndrome (MDS) showed that survival at 100 days and at two years following hematopoietic cell transplant (HCT) for patients aged... Continue Reading

Promising Survival for AML Patients Treated with Stem Cells from Related Half Matched Donor (July 30, 2015)

Patients with acute myeloid leukemia (AML) may have a promising new treatment option. Research shows that stem cell transplant from a “half matched” related donor plus chemotherapy results in similar... Continue Reading

Phase II Clinical Trial Shows Stem Cell Transplantation Effective For Severe Multiple Sclerosis Treatment (February 26, 2015)

A study published in the journal Neurology reveals that stem cell transplantation could be a more effective therapy in severe cases of multiple sclerosis (MS) than the drug mitoxantrone. The study is entitled... Continue Reading

Reduced-Intensity Stem Cell Transplant Minimizes Effects on Mental Functioning (December 20, 2013)

In contrast to full-intensity stem cell transplants, reduced-intensity stem-cell transplants appear to have little effect on cognitive function. These results were presented at the 2013 Annual Meeting... Continue Reading

Treatment with Early Stem Cell Transplant Improves Outcomes in Aggressive NHL (November 12, 2013)

Early autologous stem cell transplantation resulted in improved progression-free survival in patients with high-intermediate risk or high-risk disease who experienced a response to induction therapy, according... Continue Reading

Antiretroviral Drug May Prevent Graft-Versus-Host Disease (August 6, 2012)

The drug Selzentry® (maraviroc), which is typically used to treat HIV infection, may help prevent graft-versus-host disease (GVHD), a potentially lethal complication of stem cell transplants, according... Continue Reading

Mini-Transplants Continue to Show Promise for Older Patients with AML (November 10, 2011)

Less toxic cancer treatment followed by an allogeneic stem cell transplant is showing promise for older patients with advanced blood and bone marrow cancers such as acute myeloid leukemia (AML). These... Continue Reading

Many Patients with “Chemo Brain” Recover within Five Years (May 23, 2011)

A study of “chemo brain”—the foggy thinking and forgetfulness that patients may experience after chemotherapy—suggests that the condition improves substantially over time for a majority of patients.... Continue Reading

Complementary Therapy for Children Undergoing Stem Cell Transplant (July 19, 2010)

Complementary therapies such as massage and humor therapy may not help children cope with the potential emotional distress associated with stem cell transplantation, according to findings recently reported... Continue Reading

Kepivance Reduces Toxicity of High-dose Therapy for Multiple Myeloma (March 24, 2010)

Among patients undergoing high-dose therapy and autologous stem cell transplantation for multiple myeloma, a three-day short course of Kepivance® (palifermin) reduces the toxicity of treatment. These... Continue Reading

Allogeneic Blood Stem Cell Transplants Using Less Toxic Treatment Regimens (Minitransplants) are a Promising New Cancer Treatment Approach (November 18, 2009)

by John Barrett, M.D., Director, Bone Marrow Transplant Program, National Institutes of Health Allogeneic bone marrow or blood stem cell transplantation after intensive treatment with irradiation and/or... Continue Reading

Managing a Rare Cancer Diagnosis (November 18, 2009)

Managing a rare cancer diagnosis presents unique challenges. One survivor shares her tips for navigating the sometimes-murky waters. By Phyllis A. Domm, with Ashley and Chris Laub On January 7, I became... Continue Reading

Sun Safety During Cancer Treatment (November 18, 2009)

Shielding your skin from the sun’s potentially harmful ultraviolet (UV) rays should be a concern for everyone, especially if you spend time outdoors, but if you’re undergoing treatment for cancer,... Continue Reading

Specific Changes in Immune System Components Predict Likelihood of Fungal Infection in Allogeneic Stem Cell Transplants (October 27, 2008)

Specific Changes in Immune System Components Predict Likelihood of Fungal Infection in Allogeneic Stem Cell Transplants Changes in specific immune system components referred to as toll-like receptors (TLRs)... Continue Reading

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